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NASH Studies Unit -NAFLD & NASH Info

  • Question:Why do some people develop cirrhosis? How fast does this happen?
  • Answer:

    About a third of people with any form of chronic liver disease develop excess scar tissue throughout the liver. In some people, this “fibrosis” progresses to the point of cirrhosis.

    Cirrhosis means that there is too much scar tissue in the liver; cirrhosis has many causes such as NASH, viruses that infect the liver chronically (hepatitis B and C), alcohol abuse, excess iron in the liver, immune system damage to the liver or bile ducts, and developmental diseases.

    The development of cirrhosis is a process that usually takes decades, although some people progress over a period of several years (e.g., children who develop NASH cirrhosis).

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